Selected publications (laboratory members underlined)


1- ElAli A (2022) Endothelial caveolin at the crossroad of thrombo-inflammation coupling. EBioMedicine 86:104329 [PMID: 36332362]

2- Al-Onaizi M, Al-Sarraf A, Braysh K, Kazem F, Al-Hussaini H, Rao M, Kilarkaje N, ElAli A (2022) Impaired spatial navigation and age-dependent hippocampal synaptic dysfunction are associated with chronic inflammatory response in db/db mice. Eur J Neurosci 56:6003-6021. [PMID: 36226387]

3- Lecordier S, Pons V, Rivest S, ElAli A (2022) Multifocal Cerebral Microinfarcts Modulate Early Alzheimer’s Disease Pathology in a Sex-Dependent Manner. Front Immunol 12:813536 [PMID: 35173711]

4- Al-Onaizi MA, Thériault P, Lecordier S, Prefontaine P, Rivest S, ElAli A (2022) Early monocyte modulation by the non-erythropoietic peptide ARA 290 decelerates AD-like pathology progression. Brain Behav Immun 99:363-382 [PMID: 34343617]


1- Khaddaj-Mallat R, Aldib N, Bernard M, Paquette AS, Ferreira A, Lecordier S, Saghatelyan A, Flamand L, ElAli A (2021) SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein. Neurobiol Dis 161:105561 [PMID: 34780863]

2- Manrique-Castano D, ElAli A (2021) Neurovascular Reactivity in Tissue Scarring Following Cerebral Ischemia. In: Pluta R, editor. Cerebral Ischemia [Internet]. Brisbane (AU): Exon Publications; 2021 Nov 6. Chapter 8 [PMID: 34905313]

3- Lecordier S, Manrique-Castano D, El Moghrabi Y, ElAli A (2021) Neurovascular Alterations in Vascular Dementia: Emphasis on Risk Factors. Front Aging Neurosci 13:727590 [PMID: 34566627]


1- Menet R, Bourassa P, Calon F, ElAli A (2020) Dickkopf-related protein-1 inhibition attenuates amyloid-beta pathology associated to Alzheimer’s disease. Neurochem Int 141:104881 [PMID: 33068684]

2- Menet R, Lecordier S, ElAli A (2020) Wnt Pathway: An Emerging Player in Vascular and Traumatic Mediated Brain Injuries. Front Physiol 11:565667 [PMID: 33068684]

3- Al-Onaizi M, Al-Khalifah A, Qasem D, ElAli A (2020) Role of Microglia in Modulating Adult Neurogenesis in Health and Neurodegeneration. Int J Mol Sci 21:687 [PMID: 32961703]


1- Jean LeBlanc N, Menet R, Picard K, Parent G, Tremblay ME, ElAli A (2019) Canonical Wnt pathway maintains blood-brain barrier integrity upon ischemic stroke and its activation ameliorates tissue-plasminogen activator therapy. Mol Neurobiol 56:6521-38 [PMID: 30852795]


1- Jean LeBlanc N, Guruswamy R, ElAli A (2018) Vascular Endothelial Growth Factor Isoform-B Stimulates Neurovascular Repair After Ischemic Stroke by Promoting the Function of Pericytes via Vascular Endothelial Growth Factor Receptor-1. Mol Neurobio 55:3611-26 [PMID: 28290152]

2- Menet R, Bernard M, ElAli A (2018) Hyperlipidemia in Stroke Pathobiology and Therapy: Insights and Perspectives. Front Physiol 9:488 [PMID: 29867540]


1- Jackson S, ElAli A, Virgintino D, Gilbert MR (2017) Blood-brain barrier pericyte importance in malignant gliomas: what we can learn from stroke and Alzheimer’s disease. Neuro Oncol 19:1173-82 [PMID: 28541444]

2- Guruswamy R, ElAli A (2017) Complex Roles of Microglial Cells in Ischemic Stroke Pathobiology: New Insights and Future Directions. Int J Mol Sci 18:E496 [PMID: 28245599]


1- Thériault P, ElAli A, Rivest S (2016) High fat diet exacerbates Alzheimer’s disease-related pathology in APPswe/PS1 mice. Oncotarget 7:67808-827 [PMID: 27661129]

2- ElAli A (2016) The implication of neurovascular unit signaling in controlling the subtle balance between injury and repair following ischemic stroke. Neural Regen Res 11:914-5 [PMID: 27482215]

3- ElAli A, Rivest S (2016) Microglia Ontology and Signaling. Front Cell Dev Biol 4:72 [PMID: 27446922]

4- Thériault P, Le Béhot A, ElAli A, Rivest S (2016) Sub-acute systemic erythropoietin administration reduces ischemic brain injury in an age-dependent manner. Oncotarget 7:35552-61 [PMID: 27248662]

5- ElAli A, Jean LeBlanc N (2016) The Role of Monocytes in Ischemic Stroke Pathobiology: New Avenues to Explore. Front Aging Neurosci 8:29 [PMID: 26941641]

6- Bordeleau M, ElAli A, Rivest S (2016) Severe chronic cerebral hypoperfusion induces microglial dysfunction leading to memory loss in APPswe/PS1 mice. Oncotarget 7:11864-80 [PMID: 26918610]

7- ElAli A, Bordeleau M, Thériault P, Filali M, Lampron A, Rivest S (2016) Tissue-Plasminogen Activator Attenuates Alzheimer’s Disease-Related Pathology Development in APPswe/PS1 Mice. Neuropsychopharmacology 41:1297-307 [PMID: 26349911]

8- ElAli A, Rivest S (2016) Microglia in Alzheimer’s disease: A multifaceted relationship. Brain Behav Immun 55:138-50 [PMID: 26254232]


1- Schrewe L, Lill CM, Liu T, Salmen A, Gerdes LA, Guillot-Noel L, Akkad DA, Blaschke P, Graetz C, Hoffjan S, Kroner A, Demir S, Böhme A, Rieckmann P, ElAli A, Hagemann N, Hermann DM, Cournu-Rebeix I, Zipp F, Kümpfel T, Buttmann M, Zettl UK, Fontaine B, Bertram L, Gold R, Chan A (2015) Investigation of sex-specific effects of apolipoprotein E on severity of EAE and MS. J Neuroinflammation 12:234 [PMID: 26669675]

2- Thériault P, ElAli A, Rivest S (2015) The dynamics of monocytes and microglia in Alzheimer’s disease. Alzheimers Res Ther 7:41 [PMID: 25878730]


1- ElAli A, Thériault P, Rivest S (2014) The role of pericytes in neurovascular unit remodeling in brain disorders. Int J Mol Sci 15:6453-74 [PMID: 24743889]


1- ElAli A, Thériault P, Préfontaine P, Rivest S (2013) Mild chronic cerebral hypoperfusion induces neurovascular dysfunction, triggering peripheral beta-amyloid brain entry and aggregation. Acta Neuropathol Commun 1:75 [PMID: 24252187]

2- Zechariah A, ElAli A, Doeppner TR, Jin F, Hasan MR, Helfrich I, Mies G, Hermann DM (2013) Vascular endothelial growth factor promotes pericyte coverage of brain capillaries, improves cerebral blood flow during subsequent focal cerebral ischemia, and preserves the metabolic penumbra. Stroke 44:1690-7 [PMID: 23632977]

3- Lampron A, ElAli A, Rivest S (2013) Innate immunity in the CNS: redefining the relationship between the CNS and Its environment. Neuron 78:214-32 [PMID: 23622060]

4- Zechariah A, ElAli A, Hagemann N, Jin F, Doeppner TR, Helfrich I, Mies G, Hermann DM (2013) Hyperlipidemia attenuates vascular endothelial growth factor-induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells. Arterioscler Thromb Vasc Biol 33:1561-67 [PMID: 23559636]

5- ElAli A, Rivest S (2013) The role of ABCB1 and ABCA1 in beta-amyloid clearance at the neurovascular unit in Alzheimer’s disease. Front Physiol 4:45 [PMID: 23494712]

6- Urrutia A, Rubio-Araiz A, Gutierrez-Lopez MD, ElAli A, Hermann DM, O’Shea E, Colado MI (2013) A study on the effect of JNK inhibitor, SP600125, on the disruption of blood-brain barrier induced by methamphetamine. Neurobiol Dis 50:49-58 [PMID: 23069681]


1- Hermann DM, ElAli A (2012) The abluminal endothelial membrane in neurovascular remodeling in health and disease. Sci Signal 5:re4 [PMID: 22871611]

2- Doeppner TR, Ewert TA, Tönges L, Herz J, Zechariah A, ElAli A, Ludwig AK, Giebel B, Nagel F, Dietz GP, Weise J, Hermann DM, Bähr M (2012) Transduction of neural precursor cells with TAT-heat shock protein 70 chaperone: therapeutic potential against ischemic stroke after intrastriatal and systemic transplantation. Stem Cells 30:1297-310 [PMID: 22593021]

3- Herring A, Donath A, Steiner KM, Widera MP, Hamzehian S, Kanakis D, Kölble K, ElAli A, Hermann DM, Paulus W, Keyvani K (2012) Reelin depletion is an early phenomenon of Alzheimer’s pathology. J Alzheimers Dis 30:963-79 [PMID: 22495348]

4- ElAli A, Urrutia A, Rubio-Araiz A, Hernandez-Jimenez M, Colado MI, Doeppner TR, Hermann DM (2012) Apolipoprotein-E controls adenosine triphosphate-binding cassette transporters ABCB1 and ABCC1 on cerebral microvessels after methamphetamine intoxication. Stroke 43:1647-53 [PMID: 22426312]

5- Herz J, Reitmeir R, Hagen SI, Reinboth BS, Guo Z, Zechariah A, ElAli A, Doeppner TR, Bacigaluppi M, Pluchino S, Kilic U, Kilic E, Hermann DM (2012) Intracerebroventricularly delivered VEGF promotes contralesional corticorubral plasticity after focal cerebral ischemia via mechanisms involving anti-inflammatory actions. Neurobiol Dis 45:1077-85 [PMID: 22198574]

6- Reitmeir R, Kilic E, Reinboth BS, Guo Z, ElAli A, Zechariah A, Kilic U, Hermann DM (2012) Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain. Acta Neuropathol 123:273-84 [PMID: 22109109]

7- ElAli A, Hermann DM (2012) Liver X receptor activation enhances blood-brain barrier integrity in the ischemic brain and increases the abundance of ATP-binding cassette transporters ABCB1 and ABCC1 on brain capillary cells. Brain Pathol 22:175-87 [PMID: 21767321]


1- ElAli A, Doeppner TR, Zechariah A, Hermann DM (2011) Increased blood-brain barrier permeability and brain edema after focal cerebral ischemia induced by hyperlipidemia: role of lipid peroxidation and calpain-1/2, matrix metalloproteinase-2/9, and RhoA overactivation. Stroke 42:3238-44 [PMID: 21836084]

2- Doeppner TR, Bretschneider E, Doehring M, Segura I, Sentürk A, Acker-Palmer A, Hasan MR, ElAli A, Hermann DM, Bähr M (2011) Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia. Acta Neuropathol 122:429-42 [PMID: 21779764]

3- ElAli A, Hermann DM (2011) ATP-binding cassette transporters and their roles in protecting the brain. Neuroscientist 17:423-36 [PMID: 21518814]

4- Reitmeir R, Kilic E, Kilic U, Bacigaluppi M, ElAli A, Salani G, Pluchino S, Gassmann M, Hermann DM (2011) Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodelling and contralesional pyramidal tract plasticity. Brain 134:84-99 [PMID: 21186263]

5- Doeppner TR, Kaltwasser B, ElAli A, Zechariah A, Hermann DM, Bähr M (2011) Acute hepatocyte growth factor treatment induces long-term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation. J Cereb Blood Flow Metab 31:1251-62 [PMID: 21119693]

6- ElAli A, Hermann DM (2010) Apolipoprotein E controls ATP-binding cassette transporters in the ischemic brain. Sci Signal 3:ra72 [PMID: 20923933]


1- Zechariah A, ElAli A, Hermann DM (2010) Combination of tissue-plasminogen activator with erythropoietin induces blood-brain barrier permeability, extracellular matrix disaggregation, and DNA fragmentation after focal cerebral ischemia in mice. Stroke 41:1008-12 [PMID: 20360548]

2- Kilic E*, ElAli A*, Kilic U, Guo Z, Ugur M, Uslu U, Bassetti CL, Schwab ME, Hermann DM (2010) Role of Nogo-A in neuronal survival in the reperfused ischemic brain. J Cereb Blood Flow Metab 30:969-84 [PMID: 20087369] *equal contribution


1- Daubon T, Chasseriau J, ElAli A, Rivet J, Kitzis A, Constantin B, Bourmeyster N (2008) Differential motility of p190bcr-abl- and p210bcr-abl-expressing cells: respective roles of Vav and Bcr-Abl GEFs. Oncogene 27:2673-85 [PMID: 18059343]